CAS No. 23141-25-5

Molecular Formula: C26H30N2O8
Molecular Weight: 498.525

Description:
Strictosamide is a natural alkaloid isolated from the herbs of Nauclea latifolia, it exhibits the activity of anti-inflammatory. In vitro and in vivo, strictosamide has no effection on kidney Na(+),K(+)-ATPase, but in vivo it producesan increase of Na+,K+-ATPase activity of brain, these findings indicate thatthe compound may be related to the induction of α2 isoform of Na+,K+-ATPase.Furthermore strictosamide has nonsignificant effection on brain, but inhibite the in vitro and in vivo Mg2+-ATPase activity on kidney.

• Molecular Weight: 498.5
• Molecular Formula: C26H30N2O8

Purity: >98%

Canonical SMILES:
C=CC1C2CC3C4=C(CCN3C(=O)C2=COC1OC5C(C(C(C(O5)CO)O)O)O)C6=CC=CC=C6N4

InChI:
1S/C26H30N2O8/c1-2-12-15-9-18-20-14(13-5-3-4-6-17(13)27-20)7-8-28(18)24(33)16(15)11-34-25(12)36-26-23(32)22(31)21(30)19(10-29)35-26/h2-6,11-12,15,18-19,21-23,25-27,29-32H,1,7-10H2/t12-,15+,18+,19-,21-,22+,23-,25+,26+/m1/s1

InChIKey: LBRPLJCNRZUXLS-IUNANRIWSA-N

• Boiling Point: 816.2±65.0°C (Predicted)
• Melting Point: 176-177°C(Solv: methanol (67-56-1))
• Appearance: Powder
• Application: anti-inflammatory

Synonyms:
1,2,7,8,13,13bβ,14,14aα-Octahydro-1β-vinyl-2α-(β-D-glucopyranosyloxy)-5H-indolo[2,3-a]pyrano[3,4-g]quinolizine-5-one

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