SIS3 hydrochloride

BGC Id:	254367198562
CAS No:	521984-48-5
Synonyms:	sis3 hcl ; sis3 hydrochloride ; (2e)-1-(6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride ; sis3
Molecular Formula:	C28H27N3O3.HCl
Molecular Weight:	489.99
EINECS:

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The following 3 notable providers have been checked and can be recommended.

Dayang Chem

BOC Sciences

Description : SIS3 is a potent and specific inhibitor of Smad3 via inhibiting the effects of TGF-β1. SIS3 inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation with no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. It inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts.

Molecular Weight : 489.99
Molecular Formula : C28H27N3O3.HCl

Purity : > 98% Canonical

Amadis Chemical Company

What other providers are available for CAS 521984-48-5?

The last intensive check and update was carried out on 2025/11/26.

Identify

Synonyms:

sis3 hcl ; sis3 hydrochloride ; (2e)-1-(6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride ; sis3

CAS:

521984-48-5

EINECS:

Molecular Formula:

C28H27N3O3.HCl

MDL:

MFCD09265258

SMILES:

C1=C(C(=NC=C1Br)Br)Cl

Properties

Molecular Weight:

489.99 g·mol−1

Solubility:

Soluble in water: <2 mg/mL: DMSO: >20 mg/mL

Download Molfile for :
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline Monohydrochloride

Suppliers

Dayang Chem (Hangzhou) Co.,Ltd.

Company type: Leading producer

Hangzhou DayangChem Co. Ltd is a comprehensive entity which specializes in development, production and trade of pharmaceutical, agrochemical and dyestuff intermediates as well as some special type reagents. We have an own factory and share enterprises. We are supplier of 1,4-Ditosyl-1,4-diazepan-6-ol. We act also as agent of many chemical factories and promote their products to the international market at very competitive price. We take "Credi first, Clients supreme" as our aim. We expect to cooperate with more partners in ...

Country: P.R.China Phone: +86-571-88938639 Telefax: +86-571-8893-8652

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BOC Sciences

Company type: Supplier
Country: USA
Phone: +1-631-485-4226
Telefax: +1-631-614-7828

BOC Sciences provides a wide range of customer services, bulk and specialty compounds to the pharmaceutical, agrochemical and biotechnology industries. We intend to offer you the products and services of the highest quality at the most reasonable, cost efficient prices. Most of our compounds can be supplied ranging from mg to kg and arrive with analytic report. We sell Tenofovir disoproxil usp related compound h as well. We hope to add immense value to your research projects!

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Amadis Chemical Company Limited

Amadis Chemical is one of the leading enterprises in medical and health products research,development,manufacture and trading.rnEstablished in 2010, Amadis Chemical are adhering to the " Consummate service Convincing honor " Business strategy. The topping products and service we providing to you base on our strong technical accumulation and outstanding professional quality.rnOur associated labs, leading by the outstanding chemistry or pharmacy professors ,make us keep ahead a ...

Company type: Leading producer
Country: P.R.China
Phone: +86-571-89925085
Telefax: +86-571-89925065

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Safety Information

Hazard Classes:

Storage temperature:

2-8°C

What other providers are available for CAS 521984-48-5?

In addition to the providers presented here for SIS3 hydrochloride with the CAS number 521984-48-5, there are other 3 providers with slightly different product names available for this CAS number.

SIS3

Leap Chem Co., Ltd | BIOZOL Diagnostica Vertrieb GmbH +1 additional providers that we know from the past